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Lack of electron acceptors contributes to redox stress and growth arrest in asparagine-starved sarcoma cells

ABSTRACT: Adequate availability of the non-essential amino acid asparagine is necessary to support growth and survival of sarcoma cells. The three top pathways enriched among transcripts upregulated in asparagine-depleted cells included ribosome, aminoacyl tRNA biosynthesis and oxidative phosphorylation.

ORGANISM(S): Mus musculus

PROVIDER: GSE153991 | GEO | 2022/06/20

REPOSITORIES: GEO

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