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Transcriptome Analysis of treated cells in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia

ABSTRACT: To elucidate the transcriptomic effects of targeted therapy on Ph-like ALL cells, we performed RNA sequencing of the three Ph-like cell lines treated with venetoclax, TKI, or both drugs in combination for 72 hours. This allowed us to analyze differentially expressed genes and global transcriptomic shifts after inhibitor therapy in several Ph-like ALL models.

ORGANISM(S): Homo sapiens

PROVIDER: GSE161939 | GEO | 2021/09/22

REPOSITORIES: GEO

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