Global genomic profiling of HIF-1a-regulated genes in bone marrow B cells under hypoxia or normoxia

ABSTRACT: HIF-1a works as a stress-induced transcription factor to induce target genes mediating cell proliferation, meabolism and inflammation. To gain new insights into HIF-1a biology, we used high-throughput sequencing to analyze global HIF-1a transcriptional networks in WT or HIF-1a deficient bone marrow B cells under hypoxia or normoxia.

ORGANISM(S): Mus musculus

PROVIDER: GSE163848 | GEO | 2022/02/24

REPOSITORIES: GEO