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Gene expression profiling of CD45+CD11b+F4/80high macrophages and CD45+TCRbeta+CD8+ T cells in MC38 tumor of WT, muMt-/- or muMt-/- mice implanted with GABA pellet

ABSTRACT: We characterized the tumor-infiltrating macrophages and CD8 T cells, and we found a pro-inflammatory signature of those cells in muMt-/- mice compared to those in WT mice. Furthermore, many target genes of inflammatory cytokines, such as the TNF target genes, highly expressed in muMt-/- mice, were downregulated by exogenous of GABA.

ORGANISM(S): Mus musculus

PROVIDER: GSE169543 | GEO | 2021/09/02

REPOSITORIES: GEO

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Gene expression profiling of CD45+CD11b+F4/80high macrophages and CD45+TCRbeta+CD8+ T cells in MC38 tumor of WT, muMt-/- or muMt-/- mice implanted with GABA pellet

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