Comparison of DNA methylation profiles in diploid and transformed tetraploid MEF cells

ABSTRACT: We propose that tetraploidy induces epigentic changes including DNA methylation due to the abnormal chromatin in the cells. To test our hypothesis, we employed methylated CpG island recovery assay (MIRA) assisted microarray to determine the DNA methylation profiles in both diploid and tetraploid cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE18814 | GEO | 2012/04/30

SECONDARY ACCESSION(S): PRJNA123857

REPOSITORIES: GEO