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E. coli CFT073 gene expression at t= 4 hours after a temperature upshift from 23˚C to 37˚C (M9 minimal glycerol medium, exponential phase growth)

ABSTRACT: We investigated the effect of a temperature shift from 23˚C to 37˚C, mimicking the temperature transition experienced by a microbe as it enters a human host. This strategy allowed the exploration of gene expression changes in a short term response to a temperature upshift and to characterize the suite of genes required to respond to 37˚C in the first few hours. We demonstrate that a significant number of genes are rapidly altered in expression within hours after a temperature shift. Many of these genes are related to adhesion, immune evasion, and stress responses, suggesting that temperature may serve as a sentinel cue to predict and prepare for niche adaptation in the host.

ORGANISM(S): Escherichia coli

PROVIDER: GSE188581 | GEO | 2025/12/18

REPOSITORIES: GEO

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E. coli CFT073 protein expression at t= 4 hours after a temperature upshift from 23˚C to 37˚C (M9 minimal glycerol medium, exponential phase growth)

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