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MRNA profiling after TAC/Sham surgery in NRON KO/wt mice

ABSTRACT: The long-non coding RNA NRON is enriched in cardiomyocytes where it localizes in the nucleus. Unexpectedly, NRON-overexpression in a transverse aortic constriction-induced hypertrophy mouse model exacerbated hypertrophy, whereas cardiomyocyte-specific NRON-deletion attenuated cardiac hypertrophy, thereby suggesting a novel regulatory role of NRON in the heart.

ORGANISM(S): Mus musculus

PROVIDER: GSE188762 | GEO | 2021/11/20

REPOSITORIES: GEO

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