Gene expression effects of morpholino directed spRunt-1 knockdown on hatched blastula stage embryos

ABSTRACT: Runt domain (Runx) transcription factors constitute a metazoan family of sequence specific DNA binding proteins that are essential for animal development. The sea urchin Runx gene SpRunt-1, which is expressed globally during early embryogenesis, is required for blastula stage cell proliferation and subsequently for cell survival. To obtain a comprehensive list of SpRunt-1 regulatory targets we screened a custom microarray representing the blastula stage transcriptome of Strongylocentrotus purpuratus, comparing relative hybridization signals generated by labeled RNA from 18 hr control versus SpRunt-1 morphant embryos.

ORGANISM(S): Strongylocentrotus purpuratus

PROVIDER: GSE19751 | GEO | 2010/01/07

SECONDARY ACCESSION(S): PRJNA122219

REPOSITORIES: GEO