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Transcriptional effects of bipolar disorder drugs on NT2-N cells

ABSTRACT: Human neuronal-like cells (NT2-N) were treated with either lamotrigine (50 µM), lithium (2.5 mM), quetiapine (50 µM), valproate (0.5 mM) or vehicle control for 24 hours. Genome wide mRNA expression was quantified by RNA-sequencing. Results offer insights on the mechanism(s) of action of bipolar disorder drugs at the transcriptional level.

ORGANISM(S): Homo sapiens

PROVIDER: GSE197966 | GEO | 2022/04/08

REPOSITORIES: GEO

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