Project description:Profiling of gain and loss of DNA fragments in HHR comparing control SDR. Two analyses were performed; sample 1, SDR (male) vs HHR (male) and sample 2, SDR (female) vs HHR (female).

2013-07-13 | E-GEOD-48825 | biostudies-arrayexpress

Sprague Dawley rats: A model of successful heart aging.

Project description: Not available

| S-EPMC5988506 | biostudies-literature

microRNA profiling of Sprague Dawley organs

Project description:We performed deep sequencing of the miRNAs present in ~20 toxicologically relevant tissues in Sprague Dawley rats and used three independent analysis of the data to determine which miRNAs are tissue specific and tissue enriched. We performed deep sequencing of miRNAs in 21 organs from 5 male Sprague Dawley rats and 23 organs from 5 female Sprague Dawley rats.

2016-09-01 | E-GEOD-78031 | biostudies-arrayexpress

Control vs Diabetic Penile Tissues

Project description:Gene expression analysis in control and diabetic rats. Diabetes-induced erectile dysfunction in rat model of DM. 10 weeks of streptozotocin induced diabetes. F344 Rats. Keywords: other

2005-08-23 | GSE2457 | GEO

Investigation of the Dietary Ingestion of 2-Aminoanthracene in Sprague Dawley Rats using genomic tools.

Project description:The present research focuses on 2-aminoanthracene (2AA), recognized as a derivative of PAHs. The Centers for Disease Control and Prevention (CDC) characterizes PAHs as exhibiting properties that adversely affect the health of various living organisms. These compounds increase the risk of neoplasms in humans and animals and are implicated in the increase of genetic mutations. 2AA, an aromatic amine, has demonstrated elevated carcinogenic and mutagenic potential on animals7. In the long term, exposure to PAHs may cause damage to the liver and kidneys. Furthermore, 2AA has been associated with the onset of early diabetic symptoms9. Consumption of 2AA by Sprague-Dawley rats has shown inflammatory and genetic overregulation, increased glucose, and decreased insulin production. This study aims to examine the hepatic impact of 2AA ingestion by Sprague-Dawley Rats. Rats have anatomical structures of the organs similar to those of humans, so they are suitable for research in biomedical science.

2023-07-21 | E-MTAB-13061 | biostudies-arrayexpress

A gene catalogue of the Sprague-Dawley rat gut metagenome.

Project description: Not available

| S-EPMC5967468 | biostudies-literature