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Senohemostatic role for DPP4 in atherosclerosis

ABSTRACT: We performed scRNA sequencing to understand the composition and differential gene expression changes in aortic cells from LDLR-/- mice fed a normal diet (ND), high-fat diet (HFD), or HFD + DPP4i. We combined this technique with CITE-sequencing to measure the cell surface protein expression (DPP4) and transcriptomic changes associated with our experimental conditions as well as changes associated with DPP4 cell surface expression in all aortic cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE209525 | GEO | 2023/05/18

REPOSITORIES: GEO

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