Transcriptional regulation of ES cell by FGF signalling [RN18147]

ABSTRACT: FGF4 paracrine signaling through FGF receptors is believed to induce Erk activity and promotes the exit from pluripotency. However, we have recently observed that FGF4 and FGF2 have opposing effects on mES cell fate. The aim of this study was to understand the underlying transcriptional changes associated with these opposing actions.

ORGANISM(S): Mus musculus

PROVIDER: GSE209716 | GEO | 2025/07/25

REPOSITORIES: GEO