Genomics

Dataset Information

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Time Course Gene Expression Microarray Analysis of a Mouse B-cell Line (CH12.LX) Activated with Lipopolysaccharide and Treated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin


ABSTRACT: The objective of the study was to characterize gene expression cascade involved in the suppression of B-cell activation and differentiation by 2,3,7,8-tetrachlorodibenzo-p-dixoxin (TCDD). The underlying hypothesis was that multiple nodes in the B-cell differentiation network are directly or indirectly regulated by TCDD through its receptor, the AHR.

ORGANISM(S): Mus musculus

PROVIDER: GSE21272 | GEO | 2010/10/21

SECONDARY ACCESSION(S): PRJNA126261

REPOSITORIES: GEO

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