Transcriptomics

Dataset Information

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Effects of optogenetic and chemogenetic LC activation on the hippocampal transcriptome


ABSTRACT: The locus coeruleus noradrenergic (LC-NA) system plays an important role in organizing a physiological response to acute stress. However, if and how the LC affects stress-mediated transcriptomic changes in the brain is still barely understood. Here, we extensively characterize LC mediated transcriptomic response during acute stress in the hippocampus. Combining for the first time bulk mRNA-sequencing and selective chemogenetic and optogenetic manipulations of the LC-NA system

ORGANISM(S): Mus musculus

PROVIDER: GSE218313 | GEO | 2023/02/02

REPOSITORIES: GEO

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