Transcriptomics

Dataset Information

26

Smallpox vaccination with LC16m8 vaccinia virus provides a gene expression profile similar to DryVax vaccination


ABSTRACT: Transcriptional analysis of global gene expression changes in naïve subjects in response to smallpox vaccination with either DryVax or the replication-competent, attenuated LC16m8 vaccinia virus. Overall design: Subjects were vaccinated with either DryVax or LC16m8 (5 from each group), and blood samples were taken at days 0, 3, 7, 10, 13, and 21 post-vaccination. PBMCs were isolated from the samples, and were then further separated into cell subpopulations using positive selection against CD markers (CD4+, CD20+). There are a total of 142 samples analyzed in this dataset.

INSTRUMENT(S): SFGF HEEBO Human Set v1.00 with custom orthopox oligos

ORGANISM(S): Homo sapiens  

SUBMITTER: Judy Yen  

PROVIDER: GSE22121 | GEO | 2010-12-01

SECONDARY ACCESSION(S): PRJNA127607

REPOSITORIES: GEO

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