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SRCAP Mutations Drive Clonal Hematopoiesis Through Epigenetic and DNA Repair Dysregulation [Cut & Run]


ABSTRACT: To investigate how Srcap mutations confer mutant hematopoietic stem and progenitor cells (HSPCs) with selective advantage after transplantation We assessed SRCAP chromatin remodeling and corresponding H2A.Z incorporation using Cut-and-run sequencing

ORGANISM(S): Mus musculus

PROVIDER: GSE229864 | GEO | 2023/10/19

REPOSITORIES: GEO

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