Small molecule TERT activator prevents aging and cognitive decline [ChIP-seq]

ABSTRACT: We discovered a novel small-molecule TERT activating compound (TAC) that selectively enhances TERT transcription in human and mouse adult somatic cells. Our findings also provide the novel mechanism of TAC-mediated TERT up-regulation and elucidate the impact of TERT induction on regulatory factors governing aging.

ORGANISM(S): Homo sapiens

PROVIDER: GSE231455 | GEO | 2024/05/14

REPOSITORIES: GEO