Transcriptomics

Dataset Information

40

The effects of novel adjuvant complex and CpG ODN on host immune response to recombinant Eimeria profilin vaccine


ABSTRACT: This study investigated the ability of two novel adjuvant formulations, QCDC (Quil A/cholesterol/DDA/Carbopol) and QCDCR (QCDC/Bay R1005), in combination with a recombinant profilin vaccine, to modulate host protective immunity and to alter new gene expression during experimental avian coccidiosis. Overall design: Four-condition experiment, Profilin only vs. Non-vaccination, Profilin only vs. Co-vaccination of QCDC plus profilin, Profilin only vs. Co-vaccination of QCDCR plus profilin, Biological replicates: 2 profilin only replicates, 2 Non-vaccination replicates, 2 QCDC plus profilin replicates, 2 QCDCR plus profilin replicates with dye-switching.

INSTRUMENT(S): Agilent-015068 Chicken Gene Expression Microarray 4x44k (Feature Number version)

ORGANISM(S): Gallus gallus  

SUBMITTER: Duk Kyung Kim  

PROVIDER: GSE24966 | GEO | 2010-10-28

SECONDARY ACCESSION(S): PRJNA132011

REPOSITORIES: GEO

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