Genomics

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A Genome-wide Study of DNA Methylation Patterns and Gene Expression Levels in Multiple Human and Chimpanzee Tissues


ABSTRACT: It has long been hypothesized that changes in gene regulation have played an important role in primate evolution. However, despite the wealth of comparative gene expression data, there are still only few studies that focus on the mechanisms underlying inter-primate differences in gene regulation. In particular, we know relatively little about the degree to which changes in epigenetic profiles might explain differences in gene expression levels between primates. To this end, we studied DNA methylation and gene expression levels in livers, hearts, and kidneys from multiple humans and chimpanzees.

ORGANISM(S): Pan troglodytes Homo sapiens

PROVIDER: GSE26033 | GEO | 2011/02/25

SECONDARY ACCESSION(S): PRJNA135501

REPOSITORIES: GEO

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