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Crosstalk between human blastoids and endometrial assembloids mimicking maternal-fetal interactions and post-implantation development

ABSTRACT: We report that the three-dimensional (3D) maternal-fetal co-culture model using blastoid and endometrial assembloids captures the characteristics of embryo implantation and post-implantation development, including embryo attachment and expansion, trophoblasts differentiation, and gastrulation development. We also reveal the intricate maternal-fetal communication network.

ORGANISM(S): Homo sapiens

PROVIDER: GSE263528 | GEO | 2026/04/09

REPOSITORIES: GEO

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Crosstalk between human blastoids and endometrial assembloids mimicking maternal-fetal interactions and post-implantation development

Project description:Crosstalk between human blastoids and endometrial assembloids mimicking maternal-fetal interactions and post-implantation development

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