Transcriptomics

Dataset Information

21

Expression data from non-metastatic and metastatic osteosarcoma cells


ABSTRACT: Osteosarcoma (OS) is the malignant bone tumor with a high tendency to metastasize to the lung, where the molecular mechanisms are unclear. The mouse OS cell line LM8 has been isolated originally from the Dunn OS cell line by in vivo selection as a subline with a high metastatic potential to the lung. We used gene chip-based global gene expression analysis of differential screening between parental Dunn and LM8 cells in order to reveal genes predominantly expressed in LM8 cells, which correlate with high metastatic potential. Overall design: 2 cell lines

INSTRUMENT(S): [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

ORGANISM(S): Mus musculus  

SUBMITTER: Takeshi G Kashima   

PROVIDER: GSE26648 | GEO | 2011-03-04

SECONDARY ACCESSION(S): PRJNA136381

REPOSITORIES: GEO

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