Transcriptomics

Dataset Information

0

A first-in-class small-molecule inhibitor targeting AVIL exhibits safety and antitumor efficacy in preclinical models of glioblastoma

ABSTRACT: Compound A or DMSO treatment with GBM U87 cell samples

ORGANISM(S): Homo sapiens

PROVIDER: GSE268857 | GEO | 2025/11/18

REPOSITORIES: GEO

Json Xml

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

Genomics A first-in-class small-molecule inhibitor targeting AVIL exhibits safety and antitumor efficacy in preclinical models of glioblastoma
| PRJNA1119199 | ENA
Unknown The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.
| S-EPMC5830080 | biostudies-literature
Transcriptomics A cytoskeleton regulator AVIL drives tumorigenesis in glioblastoma
2020-06-08 | GSE95164 | GEO
Unknown Feasibility and safety of targeting mitochondria for cancer therapy - preclinical characterization of gamitrinib, a first-in-class, mitochondriaL-targeted small molecule Hsp90 inhibitor.
| S-EPMC8820820 | biostudies-literature
Unknown First-in-Class Small Molecule Degrader of Pregnane X Receptor Enhances Chemotherapy Efficacy.
| S-EPMC11584202 | biostudies-literature
Transcriptomics A First-In-Class Inhibitor of Skp1-Skp2 Interaction Has Potent Preclinical Efficacy Against Castration-Resistant Prostate Cancer
2025-06-18 | GSE244150 | GEO
Unknown Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3.
| S-EPMC6502747 | biostudies-literature
Unknown ADT-1004: a first-in-class, oral pan-RAS inhibitor with robust antitumor activity in preclinical models of pancreatic ductal adenocarcinoma.
| S-EPMC11905721 | biostudies-literature
Unknown Bottlebrush Polymer-Conjugated Melittin Exhibits Enhanced Antitumor Activity and Better Safety Profile.
| S-EPMC8784393 | biostudies-literature
Unknown The Efficacy of CB-103, a First-in-Class Transcriptional Notch Inhibitor, in Preclinical Models of Breast Cancer.
| S-EPMC10416998 | biostudies-literature