Transcriptomics

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Intestinal and mesenteric artery formation by intestine-derived prearterial endothelial cells


ABSTRACT: The cellular and molecular mechanisms mediating arterial development remain little understood for most organs. Here, we show that a small subpopulation of endothelial cells inside the intestinal villi of the embryonic mouse, characterized by the expression of endothelial cell-specific molecule 1 (Esm1/endocan), serves as an arterial progenitor population. The specification of arterial progenitors is initiated inside the villus capillary network and contributes to the formation of intestinal and mesenteric arteries during development.

ORGANISM(S): Mus musculus

PROVIDER: GSE275961 | GEO | 2025/08/29

REPOSITORIES: GEO

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