ATAC-seq of resting and anti-CD3/CD28-stimuated Jurkat cells

ABSTRACT: The majority of genetic risk variants associated with autoimmune diseases are located in chromatin regions that are accessible during T cell stimulation. To systematically investigate the dynamic changes in chromatin accessibility during T cell activation, we utilized the Jurkat cell line as a model and performed ATAC-seq on both resting and anti-CD3/CD28-stimulated Jurkat cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE276690 | GEO | 2025/09/01

REPOSITORIES: GEO