Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing [CUT&Tag]

ABSTRACT: Skin injuries heal slowly, compared to oral epithelial tissues, and often do not regenerate lost adnexa. Using a murine mouse model expressing the oral epithelial transcription factor PITX1 in the skin, we performed CUT&Tag-seq analysis in healthy skin to delinate PITX1 and histone occupancies in the skin.

ORGANISM(S): Mus musculus

PROVIDER: GSE279042 | GEO | 2026/04/27

REPOSITORIES: GEO