Transcriptomics

Dataset Information

26

ApoD modulation mouse cerebellar transcriptome


ABSTRACT: The lipocalin Apolipoprotein D (ApoD), known to protect the nervous system against oxidative stress (OS) in model organisms, is up-regulated early in the mouse brain in response to the ROS generator paraquat (PQ). However, the processes triggered by this up-regulation have not been explored. Overall design: We present here a study of the effect of ApoD on the early transcriptional changes upon OS in the mouse cerebellum using microarray profiling. ApoD-KO and transgenic mice over-expressing ApoD in neurons are compared to wild-type controls.

INSTRUMENT(S): [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array

ORGANISM(S): Mus musculus  

SUBMITTER: Gabriel Gutierrez 

PROVIDER: GSE28643 | GEO | 2011-04-16

SECONDARY ACCESSION(S): PRJNA138953

REPOSITORIES: GEO

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