High throughput RNA-seq analysis in human primary chondrocytes treated with cyproheptadine and IL-1β

ABSTRACT: Osteoarthritis is the most common joint disease. Controlling the complex pathogenesis is challenging, thus disease-modifying OA drugs (DMOADs) are not available. We identified cyproheptadine as a potential DMOAD candidate and performed bulk RNA-seq to determine its effects on the transcriptome in human primary chondrocytes in the absence or presence of IL-1β.

ORGANISM(S): Homo sapiens

PROVIDER: GSE291878 | GEO | 2025/07/11

REPOSITORIES: GEO