Effect of mechanical compression on gene expression in HEI-286 Schwann cells and pancreatic cancer cells MiaPaCa-2 and Panc01

ABSTRACT: In this study we compare transcriptional changes induced by mechanical compression in Schwann cells and pancreatic cancer cells. Human HEI-286 Schwann cells and pancreatic cancer cells MiaPaCa-2 and Panc01 were compressed at 5 μm height for 5 minutes in 6-wells static confiner (4Dcell) or uncompressed (not confined or confined in a 20 μm height space). Our data provides comparison of molecular response of Schwann cells and cancer cells to mechanical forces.

ORGANISM(S): Homo sapiens

PROVIDER: GSE292214 | GEO | 2026/05/30

REPOSITORIES: GEO