Slow RNAPII elongation facilitates early pluripotency cell transitions without reducing replication fork rates

ABSTRACT: We assess the impact of reducing transcription elongation rate during mESCs dedifferentiation, gaining insights into its effects on replication fork dynamics, gene expression, chromatin conformation, and alternative splicing.

ORGANISM(S): Mus musculus

PROVIDER: GSE293593 | GEO | 2026/03/17

REPOSITORIES: GEO