RNA-Seq Time-Course of Rat Bladder Transcriptomes Following Spinal Cord Injury

ABSTRACT: Spinal cord injury (SCI) evokes profound dysfunction in hollow organs such as the urinary bladder and gut. Current treatments are limited by a lack of molecular data to inform novel therapeutic avenues. Previously, we showed systemic treatment with the neuroprotective agent inosine improved bladder function following SCI in rats. This RNA-seq dataset captures global transcriptomic changes in the rat bladder at multiple time points following spinal cord injury (SCI). Full-thickness bladder tissues were collected from male Sprague Dawley rats at 2, 8, and 16 weeks post-complete T8 spinal cord transection, alongside non-injured controls.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE294927 | GEO | 2025/07/09

REPOSITORIES: GEO