Transcriptomics,Genomics

Dataset Information

53

Circular RNA expression alteration in rats after traumatic spinal cord injury (SCI)


ABSTRACT: To determine whether the expression levels of circular RNAs were altered and lay a foundation for future work, we used high-throughput microarray analysis to screen circular RNAs expression patterns in the spinal cord of adult rats after traumatic spinal cord injury (SCI), finally to evaluate the potential rat models as a platform for the development of novel therapeutic targets for spinal cord injury in future clinical studies. Overall six rats at 3 days post-SCI in two groups were used to perform the microarray. Overall design: Six rats were randomly assigned to two groups: rats in the sham control group (n=3) were treated with laminectomy alone without contusion; rats in the SCI group (n=3) were subjected to laminectomy plus contusion. Rats were anesthetized at 3 days post-SCI, and a 1cm long segment of spinal cord, including the injury epicenter, was dissected and collected for the experiment.

INSTRUMENT(S): 082778 Arraystar Rat CircRNA microarray V1

SUBMITTER: Chuan Qin  

PROVIDER: GSE114426 | GEO | 2018-05-15

REPOSITORIES: GEO

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