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Transcriptomic alterations induced by low-intensity ultrasound (LIUS) in OSCC.

ABSTRACT: Ultrasound therapy has emerged as a promising, non-invasive modality for cancer treatment, although its underlying mechanisms remain incompletely understood. Immunoblotting analysis revealed that low-intensity ultrasound (LIUS) alters global levels of histone modifications, including monoubiquitinated H2B (H2Bub1), H3K4me3, and H3K27me3, in oral squamous cell carcinoma (OSCC) OC3 cells. Given the pivotal role of histone marks in transcriptional regulation, we further investigated the effect of LIUS on transcriptional control in OC3 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE299007 | GEO | 2026/02/20

REPOSITORIES: GEO

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Transcriptomic alterations induced by low-intensity ultrasound (LIUS) in OSCC.

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