Transcriptomics

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RNA-Seq Profiling of Kidney Responses in Wild-Type and Angpt2 Knockout Mice Following a 3-Week Adenine Diet


ABSTRACT: Chronic kidney disease (CKD) is characterized by progressive tubulointerstitial injury, which plays a critical role in renal dysfunction. Angiopoietin-2 (Angpt2) is implicated in vascular and inflammatory processes, but its role in CKD remains unclear. In this study, we performed RNA-seq to analyze gene expression differences in the kidneys of wild-type and Angpt2 knockout mice after a 3-week adenine diet, a well-established model of tubulointerstitial injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE300746 | GEO | 2026/04/29

REPOSITORIES: GEO

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