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Single-cell RNA-seq analysis was performed on CD45-positive cells isolated from mouse mammary tumors.

ABSTRACT: Tumors derived from BP cells of mouse mammary cancer were collected after treatment with vehicle control, olaparib alone, or the combination of olaparib and an IRG1 inhibitor. CD45-positive cells were isolated from these tumors for single-cell RNA-seq analysis to investigate the impact of the combination therapy on the tumor immune microenvironment.

ORGANISM(S): Mus musculus

PROVIDER: GSE300991 | GEO | 2026/02/24

REPOSITORIES: GEO

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