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Identification of differentially expressed genes involved in the enhancement of thermosensitivity by HIKESHI knockout in human oral squamous cell carcinoma HSC-3 cells

ABSTRACT: HIKESHI has been reported to function as a nuclear carrier protein for Hsp70 under heat-stress conditions. Functional suppression of this protein has also been shown to increase the sensitivity of cancer cells to heat. However, the molecular mechanisms underlying the enhancement of thermosensitivity in HIKESHI-suppressed cells remain unclear. In this study, we identified differentially expressed genes associated with the enhancement of thermosensitivity resulting from HIKESHI knockout in human oral squamous cell carcinoma HSC-3 cells, using GeneChip® oligonucleotide microarrays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE301403 | GEO | 2025/07/08

REPOSITORIES: GEO

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| PRJNA1284938 | ENA

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