Dataset Information


Dual Role of FoxA1 in Androgen Receptor Binding to Chromatin, Androgen Signaling and Prostate Cancer [ChIP_seq, DHS_seq]

ABSTRACT: We report the dual role of FoxA1 in androgen receptor recruitment to the chromatin of androgen responsive prostate cancer cell line LNCaP-1F5 using ChIP-sequencing. Depletion of FoxA1 reprograms both androgen and glucocorticoid receptor recruitment and subsequent gene expression. The ChIP-seq has been performed using AR, FoxA1, GR, H3K4me2 antibodies. We have also mapped the DNaseI-hypersensitive sites (DHS) using deep sequencing. Overall design: Examination of AR, FoxA1, GR, H3K4me2 binding sites and DHS sites in parental and FoxA1 depleted LNCaP-1F5 cells.

INSTRUMENT(S): Illumina Genome Analyzer (Homo sapiens)

ORGANISM(S): Homo sapiens  

SUBMITTER: Olli A. Jänne  

PROVIDER: GSE30623 | GEO | 2011-09-14



Similar Datasets

2011-09-14 | E-GEOD-30623 | ArrayExpress
2011-09-13 | E-GEOD-30622 | ArrayExpress
2013-02-05 | E-GEOD-39879 | ArrayExpress
2013-02-05 | E-GEOD-39654 | ArrayExpress
2017-10-27 | PXD008056 | Pride
2014-12-12 | E-GEOD-52201 | ArrayExpress
2014-06-02 | E-GEOD-37345 | ArrayExpress
| GSE83860 | GEO
| GSE94682 | GEO
2014-01-14 | E-MTAB-1749 | ArrayExpress