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CAGE-seq Profiling of Transcription Start Site Usage in mock-infected and human cytomegalovirus (HCMV) infected human embryonic lung fibroblasts (HELF) cells at 12h and 72h post-infection (human)

ABSTRACT: CAGE-seq (Cap Analysis of Gene Expression coupled with deep sequencing) was used to map transcription start site (TSS) usage in human embryonic lung fibroblast (HELF) cells in response to infection with the human cytomegalovirus (HCMV) HAN strain. HELF cells were mock-infected or infected at a multiplicity of infection (MOI) of 3 and harvested at 12 hours post-infection (12 hpi) or 72 hours post-infection (72 hpi). This study provides genome-wide profiles of active promoters and capped 5' transcript ends to investigate dynamic changes in TSS usage during HCMV infection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE307101 | GEO | 2025/10/01

REPOSITORIES: GEO

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