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Epigenetic and transcriptional alterations in Kmt2c/Kmt2d-deficient gastric cancer [ChIP-Seq]

ABSTRACT: KMT2C and KMT2D are two of the most frequently mutated genes in gastric adenocarcinoma, yet their function in cancer initiation remains poorly understood. In this study, we developed mouse models to investigate the molecular mechanism of Kmt2c/d loss in gastric tumorigenesis.

ORGANISM(S): Mus musculus

PROVIDER: GSE317003 | GEO | 2026/04/28

REPOSITORIES: GEO

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