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Transcriptomic profiling of HaCaT cells after 24-hour exposure to Fusobacterium nucleatum-derived outer membrane vesicles

ABSTRACT: Fusobacterium nucleatum is an anaerobic Gram-negative bacterium implicated in mucosal inflammatory conditions. Outer membrane vesicles (OMVs) derived from Gram-negative bacteria are recognized as important mediators of host–microbe interactions. In this study, bulk RNA sequencing was performed to investigate global gene expression changes in HaCaT human keratinocytes following 24-hour treatment with F.n-OMVs (10 μg/mL). The dataset provides transcriptomic profiles of treated and untreated cells and serves as a resource for exploring host cellular responses to bacterial vesicles.

ORGANISM(S): Homo sapiens

PROVIDER: GSE320506 | GEO | 2026/05/15

REPOSITORIES: GEO

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The effect of blood on Fusobacterium nucleatum

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