Transcriptomics

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ScRNA-seq reveals TMEM59 regulates microlgial phagocytosis in Alzheimer’s disease


ABSTRACT: Microglia-mediated clearance of amyloid-β (Aβ) is critical for Alzheimer’s disease (AD) progression, yet the molecular regulators participating in microglial phagocytosis remain incompletely understood. Here, we identify TMEM59 as a previously unrecognized regulator of microglial Aβ clearance.

ORGANISM(S): Mus musculus

PROVIDER: GSE324258 | GEO | 2026/09/22

REPOSITORIES: GEO

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