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Choroid plexus inflammation in bipolar disorder

ABSTRACT: Postmortem human choroid plexus tissue from individuals with bipolar disorder and matched controls was analyzed using cytokine protein arrays and bulk RNA sequencing to characterize immune and barrier-related alterations. The study identifies increased pro-inflammatory signaling and reduced trophic/supportive pathways, implicating the choroid plexus as a neuroimmune interface in bipolar disorder.

ORGANISM(S): Homo sapiens

PROVIDER: GSE328018 | GEO | 2026/06/18

REPOSITORIES: GEO

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