Transcriptomics

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High-throughout sequencing of ovarian cancer cells treated with T-oligo


ABSTRACT: After treating human ovarian cancer cells ES2 with T-oligo G4+RHPS4, high-throughput sequencing technology was employed. The transcriptome analysis revealed that T-oligo G4+RHPS4 does not exert its anti-tumor effect solely through telomere dysfunction, but instead simultaneously regulates cell cycle, senescence, and metabolic-related signaling pathways, thereby synergistically inducing the death of ovarian cancer cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE328508 | GEO | 2026/04/23

REPOSITORIES: GEO

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