A skull bone marrow-glymphatic-brain axis mediates CD8 T cell trafficking and involvement in post-ischemic stroke injury 01
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ABSTRACT: Here, we identify a skull bone marrow (SBM)-glymphatic-brain axis that mediates the trafficking and delivery of cytotoxic CD8 T cells into the ischemic brain parenchyma in human AIS. Single-cell transcriptomic profiling of patients with AIS identifies the SBM as a dynamically responsive CD8 T cell reservoir that is transcriptionally distinct from peripheral blood.
ORGANISM(S): Homo sapiens
PROVIDER: GSE331114 | GEO | 2026/05/20
REPOSITORIES: GEO
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