Bulk RNAseq analysis of wildtype and Pim1-/- macrophages

ABSTRACT: PIM1 is a serine/threonine kinase that modulates immune responses and cellular metabolism. To examine the function of PIM1 in macrophage gene expression, peritoneal macrophages were isolated from wild-type and Pim1-/- mice. They were treated with 20 μg/mL oxidized low-density lipoprotein for 8 hours. Total RNA was extracted and analyzed using bulk RNA sequencing to compare gene expression profiles and identify differentially regulated pathways between wild-type and Pim1-/- macrophages.

ORGANISM(S): Mus musculus

PROVIDER: GSE335106 | GEO | 2026/06/15

REPOSITORIES: GEO