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The FGF4–integrin β1 axis orchestrates diabetic wound regeneration by restoring directional collective motility.

ABSTRACT: This dataset was generated to investigate the mechanisms underlying the pro-healing effects of Fibroblast Growth Factor 4 (FGF4) on diabetic wounds. We performed RNA sequencing on wound tissues from streptozotocin (STZ)-induced diabetic mice. The mice received daily topical applications of either recombinant FGF4 (rFGF4) or PBS vehicle control. Wound tissues were harvested on day 7 post-wounding for transcriptomic analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE335568 | GEO | 2026/06/18

REPOSITORIES: GEO

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The FGF4–integrin β1 axis orchestrates diabetic wound regeneration by restoring directional collective motility

Project description:This dataset was generated to investigate the mechanisms underlying the pro-healing effects of Fibroblast Growth Factor 4 (FGF4) on diabetic wounds. We performed RNA sequencing on wound tissues from streptozotocin (STZ)-induced diabetic mice. The mice received daily topical applications of either recombinant FGF4 (rFGF4) or PBS vehicle control. Wound tissues were harvested on day 7 post-wounding for transcriptomic analysis.

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