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Gene expression of activated CD8+ Tc1 and Tc2 cells

ABSTRACT: RNA sequencing identified distinct transcriptional programs associated with Tc2 cell metabolism, including enhanced lipid metabolism and monoamine oxidase A (MAOA)-mediated serotonin catabolism. These data provide a resource for investigating the molecular regulation of human Tc2 cells and their role in type 2 immune responses and allergic disease. Due to restrictions in participant consent and the approved EU ethical approval (Swedish Ethical Review Authority), raw sequencing data (FASTQ files) cannot be deposited in a public repository.

ORGANISM(S): Homo sapiens

PROVIDER: GSE336578 | GEO | 2026/07/01

REPOSITORIES: GEO

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