Transcriptomic profiling of THP-1-derived M2-like macrophages under normoxia and hypoxia

ABSTRACT: Hypoxia is a key feature of the tumor microenvironment and can alter macrophage phenotypes. This study characterized hypoxia-induced transcriptional changes in THP-1-derived M2-like macrophages. Paired-end bulk RNA sequencing was performed on macrophages cultured under normoxia or hypoxia, with three biological replicates per condition. The dataset enables analysis of hypoxia-associated macrophage transcriptional programs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE344137 | GEO | 2026/08/18

REPOSITORIES: GEO