Transcriptomics,Genomics

Dataset Information

29

Follicular lymphoma lymph node


ABSTRACT: 24 independent follicular lymphoma lymph node samples on LC microarrays was used to generate the gene lists in tables 2 and 3 of publication patients were divided into two groups, rituximab responders (composed of CR and PR) and non-responders (composed of NR and MR). Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Keywords: Logical Set Overall design: Using regression correlation

INSTRUMENT(S): LC-23

SUBMITTER: Stanford Microarray Database  

PROVIDER: GSE3647 | GEO | 2005-11-23

SECONDARY ACCESSION(S): PRJNA104843

REPOSITORIES: GEO

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Publications

Variation in gene expression patterns in follicular lymphoma and the response to rituximab.

Bohen Sean P SP   Troyanskaya Olga G OG   Alter Orly O   Warnke Roger R   Botstein David D   Brown Patrick O PO   Levy Ronald R  

Proceedings of the National Academy of Sciences of the United States of America 20030205 4


Analysis of the patterns of gene expression in follicular lymphomas from 24 patients suggested that two groups of tumors might be distinguished. All patients, whose biopsies were obtained before any treatment, were treated with rituximab, a monoclonal antibody directed against the B cell antigen, CD20. Gene expression patterns in the tumors that subsequently failed to respond to rituximab appeared more similar to those of normal lymphoid tissues than to gene expression patterns of tumors from ri  ...[more]

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