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Methylation in Taiwanese HCC tumor and adjacent tissues

ABSTRACT: We analyzed tumor and adjacent non-tumor tissues from 62 Taiwanese HCC cases using Illumina HumanMethylation 27 chips. After Bonferroni adjustment, a total of 2,324 CpG sites significantly differed in methylation level, with 684 CpG sites significantly hypermethylated and 1,640 hypomethylated in tumor compared to non-tumor tissues. Array data were validated with pyrosequencing in a subset of 5 of these genes; correlation coefficients ranged from 0.92 to 0.97.

ORGANISM(S): Homo sapiens

PROVIDER: GSE37988 | GEO | 2012/05/16

SECONDARY ACCESSION(S): PRJNA167029

REPOSITORIES: GEO

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