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Expression data from U2OS ER-E2F1 cells after FOXO knockdown and E2F1 activation

ABSTRACT: Effect of FOXO knockdown on E2F1-mediated transcription

ORGANISM(S): Homo sapiens

PROVIDER: GSE39136 | GEO | 2012/07/06

SECONDARY ACCESSION(S): PRJNA170072

REPOSITORIES: GEO

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Expression data from U2OS ER-E2F1 cells after FOXO knockdown and E2F1 activation

Project description:Effect of FOXO knockdown on E2F1-mediated transcription U2OS cells stably expressing ER-E2F1 were infected with two different lentiviruses both targeting FOXO1 and FOXO3 or control virus encoding scrambled sequence. Twenty four hours post infection medium was replaced to serum-free DMEM for 24 hours. Then medium was replaced to serum-free DMEM with or without 20 nM 4-hydroxy tamoxifen for 6 hours.

2012-07-05 | E-GEOD-39136 | biostudies-arrayexpress

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Project description:Expression data from U2OS ER-E2F1 cells after FOXO knockdown and E2F1 activation

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E2F1 ChIP-Seq on mouse hepatocytes overexpressing E2F1

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Foxo signaling declines with age

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